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A bone marrow transplant is a procedure that infuses healthy blood-forming stem cells into your body to replace bone marrow that's not producing enough healthy blood cells. A bone marrow transplant is also called a stem cell transplant. Bone marrow is the soft, fatty tissue inside your breastbone and pelvic bonesis a lifesaving procedure used to treat severe blood disorders, immune system deficiencies, and certain types of cancer. The transplant replaces damaged or diseased bone marrow with healthy stem cells, helping the body produce new blood cells and restore the immune system.