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CAR T-cell therapy has involved modifing the patient’s T cells to express CARs to recognize to attack cancer cells , leading to their destruction.otherapy harnesses the body’s immune system to target and destroy cancer cells.Activated CAR T cells releases substances like cytokines, perforin, Granzymes. It has shown remarkable efficiency in treating some blood cancers such as leukomia, lymphoma, with high remission rates.CAR T-cell encounters a cancer cell expressing the target antigen, triggering the T-cell to become activated and multiply.